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Wednesday July 5, 8:32 am Eastern Time Company Press Release Shaman.com Launches DiarrheaSolutions.com — a Resource Center for People Who Suffer From Diarrhea SOUTH SAN FRANCISCO, Calif.–(BW HealthWire)–July 5, 2000– Shaman.com, the main operating division of Shaman Pharmaceuticals, Inc. (OTCBB:SHPH.OB – news), today launched DiarrheaSolutions.com, a site that provides educational information and resources to people who suffer from various types of diarrhea as a result of Irritable Bowel Syndrome (IBS), international travel, cancer treatments, Crohn’s Disease, colitis, and those experiencing diarrhea as a side effect of prescription medications. The DiarrheaSolutions.com Learning Center contains an extensive collection of links with information on managing diarrhea and includes features such as message boards, chat rooms, support groups, newsgroups, personal stories and testimonials, professional articles and information on current treatments. The site will host an online discussion forum where users can discuss gastrointestinal related topics 24 hours a day. “By adding the new Learning Center to Shaman’s network, we are now able to help the diarrhea health community share experiences and learn solutions to this debilitating problem that threatens quality of life,” said Lisa Conte president and CEO of Shaman.com. The new site is part of Shaman’s expanded commercialization strategy to promote Normal Stool Formula(TM) (NSF). Due to the highly symptomatic nature of this condition and lack of acceptable solutions, Shaman.com feels the Learning Center will greatly assist the sales of NSF. The bricks and mortar component of this strategy to date has included the recent expansion of availability of NSF in CVS ProCare retail shops, Stadtlanders, Statscript, in addition to the 1100 Medicine Shoppe pharmacies nationwide. NSF is a natural dietary supplement shown in clinical trials to be safe and effective in treating diarrhea, without causing constipation or other side-effects. DiarrheaSolutions.com is hosted by Value Web, a leading provider of web site hosting and uses Miva e-commerce software. Unlimited bandwidth and disk space ample enough to hold ten’s of thousands of pages, will allow Shaman to reach more consumers looking for natural and effective solutions to diarrhea. Normal Stool Formula, a natural botanical dietary supplement that controls diarrhea is a standardized extract from the sap of the Croton lechleri tree, which has been used for centuries by traditional healers in the Amazon rainforest to control diarrhea. Unlike most commonly available treatments, which work by reducing bowel motility and often causing uncomfortable constipation, NSF, normalizes excess water flow in the bowel and promotes normal stool formation without causing constipation. Shaman Pharmaceuticals, Inc., through its main operating division, Shaman.com is a leader in medicinal plant research and commercialization of proprietary dietary supplements. Shaman.com works collaboratively with indigenous communities to discover, harvest and reforest medicinal plants. This press release contains, among other things, certain statements of a forward-looking nature relating to Shaman’s ability to advance its development and research programs. Such statements involve a number of risk and uncertainties including the Risk Factors listed in the Shaman Pharmaceuticals, Inc.’s Annual Report on Form 10K and 10K/A for the year ended December 31, 1999. These filings are available upon request at 650/952-7070. Also visit Shaman at http://www.Shaman.com.

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